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- Rapid Novorhttps://www.rapidnovor.com/services/antibody-sequencing/Antibody Sequencing Service - Amino Acid Sequence in 2 WeeksJan 22, 2025 ... Protein de novo Antibody Sequencing determines the amino acid sequence of monoclonal antibodies using mass spectrometry. Our proprietary ...
- ACS Publicationshttps://pubs.acs.org/doi/10.1021/acs.jproteome.1c00169Mass Spectrometry-Based De Novo Sequencing of Monoclonal ...Jun 14, 2021 ... Antibody sequence information is crucial to understanding the structural basis for antigen binding and enables the use of antibodies as ...
- https://www.nature.com/articles/s41467-024-53105-8De novo protein sequencing of antibodies for identification of ...Oct 10, 2024 ... Here we present a method for sequencing human plasma-derived polyclonal IgG using a combination of mass spectrometry and B-cell sequencing.
- https://www.biorxiv.org/content/10.1101/2024.12.23.630060v1.full-textDo-it-yourself de novo antibody sequencing workflow that achieves ...Dec 23, 2024 ... We describe a workflow that enables accurate sequence determination of monoclonal antibodies based on mass spectrometry data and freely available software ...
- ACS Publicationshttps://pubs.acs.org/doi/10.1021/acs.analchem.2c01300Template-Based Assembly of Proteomic Short Reads For De Novo ...Jul 14, 2022 ... This large sequence diversity within and between individuals requires dedicated de novo sequencing of antibodies to uncover the structural basis ...
- PubMed Central (PMC)https://pmc.ncbi.nlm.nih.gov/articles/PMC8256418/Mass Spectrometry-Based De Novo Sequencing of Monoclonal ...Antibody sequence information is crucial to understanding the structural basis for antigen binding and enables the use of antibodies as therapeutics and ...
- https://www.creative-biolabs.com/next-generation-antibody-sequencing.htmlDe Novo Sequencing Services - Creative BiolabsGeneral Workflow for Antibody Sequencing · Antibody protein is initially digested into overlapping peptides using various trypsin · Digestion with LC-MS/MS, then ...
- PubMedhttps://pubmed.ncbi.nlm.nih.gov/36545804/Comprehensive evaluation of peptide de novo sequencing tools for ...Jan 19, 2023 ... Sequence information of antibodies is helpful for understanding antibody-antigen interactions and ensuring their affinity and specificity. De ...
- PubMed Central (PMC)https://pmc.ncbi.nlm.nih.gov/articles/PMC9225641/A perspective toward mass spectrometry-based de novo sequencing ...Jun 14, 2022 ... To determine the antibody sequences de novo, all these software tools require large numbers of overlapping peptides, spanning the entire ...
- https://www.proteinmetrics.com/products/de-novo-sequencing-workflowsDe Novo Sequencing WorkflowsThe de novo sequencing workflow allows you to determine the sequence of unknown antibodies using only LC-MS/MS data.
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